LZ-8 is a protein originally isolated from one of the most popular Chinese medicinal fungus (Ganoderma lucidum) and can stimulate cytokines including INF-gamma even on oral dosing. In small dosage (100 mg/kg or less) it can increase the animal body weight very significantly. This is a very promising alternative for antibiotics now serving as additives in pig/cattle poultry farms. LZ 8 can be developed as immune stimulator for the human market as a dietary supplement.
Hepasim® new drug development partnership or licensing: Hepasim® is an anti-inflammatory/anti-fibrosis compound from the mycelia of Antrodia camphorata AC is not a traditional biosimilar but may be a candidate as an NCE. This has already been proven to be an anti-inflammatory agent an HCV protease inhibitor and a potent anti-fibrosis compound. Hepasim®-rich ACM can be an excellent dietary supplement or a “Botanical Drug” candidate and has 2 clinical trials ongoing at the moment. The high Hepasim® content (~15%) inside this dietary supplement gives a partner the ability to not only prove the safety but also the effectiveness of the mycelia and the Hepasim® via human clinical study.
HERPEPS (CRO, CMO and licensing) is a platform technology developed by the Company. It can be used to produce ‘non GMP and non human use products (industrial enzymes, protein A for laboratory use). Simpson Biotech accepts gram level orders for recombinant proteins based on the HERPEPs platform and will consider licensing the platform. HERPEPs can also be licensed for particular products or markets.
HERPEPSTM High Efficiency Recombinant Protein Expression and Purification System Services
AFP License Services including Exclusive, Non-Exclusive, or Field of Use License of AFP
Manipulation of AFP-integrated target protein to ptimize protein absorption/purification (ODM)
Small-Scale Fermentation for efficacy verification
Large-Scale OEM/ODM fermentation of Recombinant Protein producing tailor-made Recombinant Proteins or Enzymes
Industrial Scale Turnkey Technology Transfer
SB-X as promising alternative for antibiotics now serving as additives in pig/cattle poultry farms. SB-X can be developed as immune stimulator for the human market as a dietary supplement and animal health products.